Gluten-Free Meatloaf

Prep 10 minutes
Cook 1 hour 15 minutes
Servings 8 servings

This gluten-free meatloaf is just like my mom used to make it with a sweet and tangy glaze topping. Juicy and tender meat packed with a flavorful seasoning mix and gluten-free breadcrumbs to make the classic loaf shape.

Two slices of glazed gluten-free meatloaf served with creamy mashed potatoes and green peas on a white plate, showcasing a comforting homemade meal.

Gluten-free meatloaf is one of my family’s favorites, inspired by my mom. I have been making meatloaf since I was a teen, and I am thrilled to share my tried-and-true recipe for classic meatloaf made gluten-free with you. Over the years, I’ve perfected this recipe to make it not only gluten-free, but also foolproof for any cook.

My gluten-free meatloaf recipe is super easy to make, perfectly seasoned, and topped with a sweet and tangy glaze that takes it to the next level. You won’t get a dry or flavorless meatloaf with my recipe—just a comforting, delicious dish that’s sure to become a family favorite in your home, too.

4.97 from 54 votes

Gluten-Free Meatloaf

Servings: 8 servings
Prep: 10 minutes
Cook: 1 hour 15 minutes
Total: 1 hour 25 minutes
Two slices of glazed gluten-free meatloaf served with creamy mashed potatoes and green peas on a white plate, showcasing a comforting homemade meal.
This gluten-free meatloaf is just like my mom used to make it with a sweet and tangy glaze topping. Juicy and tender meat packed with a flavorful seasoning mix and gluten-free breadcrumbs to make the classic loaf shape.
Step-by-step photos can be seen below the recipe card.
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Ingredients 

Seasoning Blend

  • 2 tablespoons dried chopped onion
  • 1 tablespoon onion powder
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon dried thyme
  • 1/2 teaspoon dried oregano
  • 1 teaspoon dried parsley
  • 1/4 teaspoon paprika
  • 1 teaspoon salt
  • 1/4 teaspoon pepper

Glaze

  • 3/4 cup ketchup
  • 1/4 cup brown sugar
  • 1/2 teaspoon ground mustard

Instructions 

  • Preheat oven to 350°F. Line an 8×4-inch loaf pan with parchment paper if you do not want to slice the meatloaf in the pan.
  • In a large bowl, stir together the whisked egg, breadcrumbs, seasoning mix, Worcestershire sauce, and milk and let sit for 2-3 minutes.
  • Add the ground beef to the breadcrumb mixture, and use your hands to mix together to fully combine. Do not overmix the meat or the meatloaf will be tough.
  • Add the meat mixture to a loaf pan. Pat the meat down into an even layer.
  • In a small bowl, stir together the glaze ingredients. Pour the glaze on top of the meatloaf and spread it into an even layer.
  • Bake on the middle rack for 1 hour and 15 minutes for an 8×4. or until the internal temperature reaches 160°.
  • Let the meatloaf rest for 10 minutes before cutting and serving.

Notes

  • For a dairy-free option, use unsweetened almond milk, cashew, oat, or coconut milk.
  • I use an 8×4-inch glass loaf pan for my meatloaf, but I have tried it with a 9×5-inch loaf pan. If your pan is wider, it has less depth, so you will have to adjust the cooking time. When I used the 9×5-inch pan, I cooked it for 1 hour.
  • You can also shape the meatloaf into a log and bake it on a baking sheet If you don’t have a loaf pan.
  • If you slice it while it is still too hot, it may fall apart. I always let my meatloaf cool for 10 minutes before slicing it.
  • Allow the breadcrumb mixture to sit for 2-3 minutes before adding the beef. This step helps keep your meatloaf from being too dry.
  • If you want to prepare your meatloaf beforehand, just assemble it like normal, except for adding the glaze. Cover the meatloaf with plastic wrap and place it in the refrigerator. When ready, remove it from the refrigerator, add the glaze to the top of the loaf, and bake as directed.
  • The meatloaf is fully cooked when the internal temperature reaches 160°F. If your meatloaf is a little pink but is 160°F, the meatloaf is ready to eat.
  • Store any leftovers in an airtight container in the refrigerator for 3-4 days. Reheat in the microwave until heated through.

Nutrition

Serving: 1servingCalories: 233kcalCarbohydrates: 25gProtein: 21gFat: 6gSaturated Fat: 2gPolyunsaturated Fat: 0.4gMonounsaturated Fat: 2gTrans Fat: 0.3gCholesterol: 77mgSodium: 621mgPotassium: 457mgFiber: 1gSugar: 13gVitamin A: 201IUVitamin C: 3mgCalcium: 45mgIron: 3mg

Nutrition information is automatically calculated, so should only be used as an approximation.

Additional Info

Course: Dinner, Main Course
Cuisine: American
Tried this recipe?Mention @mamaknowsglutenfree or tag #mamaknowsglutenfree!

How to Make Gluten-Free Meatloaf Step-by-Step

Gluten-free meatloaf ingredients

Gather all your ingredients together.

A mixing bowl containing a crumbly breadcrumb mixture, part of the preparation process for gluten-free meatloaf.

Preheat the oven to 350°F and line an 8×4-inch loaf pan with parchment paper. If you’re okay with slicing your meatloaf in the pan, skip this step. Whisk 1 egg and add it to a large mixing bowl. Mix in 1 cup of gluten-free breadcrumbs, 2 tbsp dried chopped onion, 1 tbsp onion powder, ½ tsp garlic powder, ½ tsp thyme, ½ tsp dried oregano, 1 tsp dried parsley. ¼ tsp paprika, 1 tsp salt, ¼ tsp black pepper, 2 tbsp Worcestershire sauce, and ¼ cup milk (or dairy-free alternative). Let the mixture sit for 2-3 minutes to allow the breadcrumbs to soak up the moisture.

A mixing bowl with raw gluten-free meatloaf mixture, fully combined and ready for shaping.

Use your hands to mix in 1 ½ lbs of lean ground beef to the breadcrumb mixture. Mix until fully combined, but do not overwork the meat. Overmixed meat will become tough.

A loaf pan lined with parchment paper, filled with the raw gluten-free meatloaf mixture, shaped and ready for baking.

Place the meat mixture into the loaf pan and pat down to an even layer.

A bowl of sweet and tangy glaze mixture, ready to be spread on the meatloaf.

Make the glaze in a small bowl. Mix together ¾ cup ketchup, ¼ cup brown sugar, and ½ tsp ground mustard. 

The raw gluten-free meatloaf in a parchment-lined loaf pan, topped with a layer of sweet and tangy glaze before baking.

Pour the glaze over the top of the meat mixture.

Freshly baked gluten-free meatloaf in a parchment-lined loaf pan, showing a glossy and caramelized glaze.

Place the loaf pan in the preheated oven on the middle rack. Bake the meatloaf for 1 hour and 15 minutes. The internal temperature should reach 160°F.

A sliced gluten-free meatloaf on a wooden cutting board, revealing the moist interior and glossy glaze on top.

Remove the loaf from the oven and let it cool for 10 minutes before slicing. Serve and enjoy!

A white plate with two slices of glazed gluten-free meatloaf, creamy mashed potatoes, and green peas, accompanied by a fork and knife, with a cloth napkin and another plate in the background.

Serving Suggestions

I always serve this to my family with my gluten-free mashed potatoes and steamed peas, because that’s how my mom did it. Serve it with your favorite style of potatoes or any vegetable of your choice. Add a crustless apple pie for dessert for a meal that feels truly special.

Storage Instructions

Store any leftovers in an airtight container in the refrigerator for 3-4 days. Reheat in the microwave until heated through. 

You can freeze meatloaf either before or after baking. For unbaked meatloaf, wrap it in foil or plastic wrap, place it in a freezer bag, and freeze for up to 3 months. Defrost it in the refrigerator overnight, add the glaze, and bake as directed. For baked meatloaf, let it cool completely before wrapping it in foil or plastic wrap, placing it in a freezer bag, and freezing for up to 3 months. Defrost in the refrigerator overnight and reheat in the microwave or oven.

A serving of gluten-free meatloaf on a black plate with mashed potatoes and green peas, with a fork cutting into the meatloaf.

More Gluten-Free Dinner Recipes

About Audrey Roberts

I'm Audrey Roberts, a busy mama of four and I love sharing the recipes that I make for my family. I make gluten-free family-friendly recipes that are simple and delicious that you can too! I use easy to find ingredients that won't break your budget. You will also find dairy-free options and Paleo recipes. I am also the author of The Everything Gluten-Free & Dairy-Free Cookbook, which is an Amazon Best Selling Cookbook in the US and Internationally. Living gluten-free since 2010. I hope by me sharing my journey it may help you with yours.

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4.97 from 54 votes
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Dea Brayden
February 4, 2026 5:51 pm

Really yummy! I made a double batch because 3# packs of ground beef were on sale. I baked half. The other half I popped in plastic wrap and in a freezer bag, with a sticky note inside the bag too with instructions for the glaze and cooking. Thanks for this recipe.

Lisa Alexander
January 12, 2026 11:13 am

I will double the glaze next time and add 1 Tbs apple cider vinegar.

Sarah Noreen
January 5, 2026 4:54 pm

love your recipes

Kruegs
December 18, 2025 1:03 pm

I shocked everyone when I told them after they were done eating it was gluten free! it tasted great and easy to make!

Janice
November 14, 2025 4:15 pm

Just making meatloaf this evening and figure I should drop a comment to say I use your recipe often, and we love it.

Thank you!
Janice

Carol A. Barrett
September 11, 2025 1:09 pm

Can I use oatmeal instead of the breadcrumbs?

Amy - Mama Knows Gluten Free
September 16, 2025 11:50 am

Hi Carol, we haven’t tested oatmeal in this recipe.

Liz
July 23, 2025 10:47 pm

Gluten Free and dairy free came out tasty and great ❤️ Really good recipe for the family.

pamela
June 25, 2025 3:53 pm

This meatloaf was absolutely delicious. My Texan husband loved it, my picky 3 year old loved it, and I loved it. I will make it this way from now on!

Cindy Brown
May 10, 2025 6:57 pm

DELICIOUS!!! Thank you for sharing! 🙂

Bee
January 28, 2025 8:53 am

I recently started my gluten free journey and this meatloaf was delicious! My hubby and kids liked it and said this was the best meatloaf I’ve ever made! Definitely my new go to recipe. Can’t wait to try more of your recipes. Thanks for sharing them!